The Indigenous and Hispanic peoples of the territory dealt with illness by combining long traditions of religious and spiritual healing with the use of natural resources that the land provided, including native herbs and plants.

Historically, in the 1880;s, the Indigenous and Hispanic peoples in the New Mexico area combined traditions of religious and spiritual healing with the use of native herbs and plants, with almost no scientific studies made.

Some of the medicinal plants used are:

Sand sage or Romerillo (Artemesia Filifolia)

Four-Wind Saltbush or Chamiso (Atriplex Canescens)

Rabbitbrush or Chamiso Blanco (Chrysothamnus Nauseosus)

Doveweed, Texas Croton or Barbasco (Croton Texensis)

Jimson Weed or Toloache (Datura mteloides)

Mormon Tea or Canutillo del campo (Ephedra Torreyana)

Buckwheat (Erioganum sp.)

Apache Plume or Ponil (Fallugia Paradoxa)

Snakeweed or Escoba de la vi Bora (Gutierrezia Sarothrae)

One-Seed Juniper or Rama de Sabina (Juniperus Monosperma)

Wolfberry or Tomatillo or Chico (Lycium Pallidum)

Wild Four O’Clock or Maravilla (Mirabilis Multiflorum)

Scorpionweed (Phacelia sp.)

Purslane (Portulaca sp.)

Three-Leaf Sumac, Lemonade Bush or Lemita (Rhus Trilobata)

Dock or Cana Agria (Rumex Hymenosepalus)

Horse Nettle or Tomatillo del Campo (Solanum Elaeagnifolium)

Globe Mallow or Yerba del Negro (Sphaeralcea Angustifolia)

Indian, Navajo, or Hopi Tea or Cota (Thelesperma Megapotamicum)

Prodigiosa Brickellia